Project 1

In vitro and in silico investigation of work-related MSD indicators on a macroscopic scale

The knowledge on physiological changes on the musculoskeletal system because of work related tasks is of high importance to improve work safety. Until today, the understanding of macroscopic and microscopic changes that stimulate the onset of degenerative changes is limited. Therefore, this subproject aims to find unfavourable loading conditions and possibilities to improve the workers’ safety. To achieve this, in vitro and in silico experiments will be conducted for spine specimens over a live time of a human. The effect of different loading conditions during work related tasks – especially of production work with high workloads – will be analysed from a macroscopic scale. The aim of Project is to quantify the effect of variances in load conditions, e.g. motion speed and range of motion, on the development of different musculoskeletal diseases based on in vitro experiments and finite element simulations. In particular, it is investigated to what extent working conditions contribute to the occurrence of work-related MSD and which adjustments of the workplace or movement patterns lead to significant changes in this respect.


RWTH Aachen University, Institute of General Mechanics


Uniklinik RWTH Aachen, Department of Orthopaedics
RWTH Aachen University, Institute of Industrial Engineering and Ergonomics